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Image SXM is a version of the public domain image analysis software NIH Image that has been extended to handle the loading, display and analysis of scanning microscope images.

Image SXM is a tool that supports SAM, SCM, SEM, SNOM, SPM, SFM, SLM, and STM images from the following systems:
· Burleigh Instruments
· Digital Instruments NanoScope II/III/IV
· DME Rasterscope/Surface Data File
· Gatan DigitalMicrograph
· JEOL JSM/WinSem/WinSPM
· JPK Instruments
· Klocke Nanotechnik Atomikro
· Leica TCS
· LEO SEM
· Molecular Imaging PicoScan
· Nanotec Electronica WSxM
· Noran Instruments Vantage
· NT-MDT
· Omicron SCALA
· Oxford Instruments TOPSystem
· Park Scientific Instruments HFS-LIF/HDF
· Philips SEM
· Quesant Instruments
· RHK Technology SPM-32
· Seiko Instruments (SIINT) SPI
· ThermoMicroscopes
· TopoMetrix SPMLab
· Unisoku
· Vacuum Generators SAM
· WA Technology
· Zeiss LSM

In addition, the following non-SXM file formats are also supported:
· AVI
· Bio-Rad
· BMP
· FITS
· Omicron SPA-LEED
· PDSF
· PDSS
· Philips APD
· SBIG CCD
· SiM-Camera
· SPEC
· Targa TGA
· UBM
· Wyko OPD

Changes from previous version

· Support has been added for Nanosurf SPM images with both easyScan (.ezd) and Nanosurf Image Document (.nid) file formats.
· Updated support for RHK Technology XPM Pro SPM images.
· Recoded some menu handling routines to avoid a crash on PowerMacs running Leopard. Intel macs running Leopard and PowerMacs running Puma/Jaguar/Panther/Tiger were unaffected.
· Fixed a bug which affected zooming of windows whose width or height was an odd value.
· Asylum Research SPM images with large footers (> 32 Kb) would not have the correct z calibration.
· Added options for Omicron SCALA images so that opening a forward (backward) scan image will automatically open the corresponding backward (forward) scan image if the file exists in the same folder. If both images are opened they are displayed as a two–image stack. These options are set in the SPM Options dialog under Show Options Specific To: Omicron SCALA.
· Added option to SXM Options to use a default colour look-up table (LUT) for every image. To set the default LUT, select the LUT from Options/Color Tables and then save the preferences file from File/Record Preferences or SXM Preferences. If this option is not selected then the image will be displayed with the LUT saved in the file or, if there isnt one, with the current LUT (note that in the latter case this can give odd results with PICT images).
· Added option to SXM Options to use a default preset spatial calibration for every image. The default scale is selected from a popup menu, which displays the same presets as the Analyze/Preset Scale submenu. If selected, the preset scale will override any spatial calibration defined for the image, so use only if you are sure that you want a fixed spatial scale.
· Colour LUTs can now be selected by pressing the caps lock key and tabbing (or shift-tabbing) between LUTs.
· Changes to Parasite Counting Analysis to improve the calculation of the multiplicity of touching parasites and the handling of structured background in images of parasites with no cells.
· Reinstated browsing of selected images (dropped when browsing was modified to use stacks in v1.85). Option-click to deselect an image. Press the option key and select Browse Selected Images from the File or SEM or SPM/Files menus to redisplay a browse window without the deselected images.
· After browsing a folder, and optionally deselecting some images by option-clicking, the images can be opened by pressing shift and selecting Open Browsed Images from the File or SEM or SPM/Files menus. If all the images are the same size, they will be opened as a stack. Otherwise they will open in separate windows, as if the user had double-clicked on each thumbnail.
· When nudging a rectangular region of interest (ROI) using the cursor keys, or stretching it using option-cursor keys, the coordinates of the corners and the width and height are displayed in the Info window.